ea0063gp64 | Reproductive Axis | ECE2019
Georgescu Carmen Emanuela
, Vonica Camelia
, Ilie Ioana Rada
, Moraru Corina
, Pop Dana
, Hazi Georgeta
, Pinzariu Oana
, Socaciu Carmen
Background: Metabolomics profiling of bio-fluids suggests altered signatures in patients with the polycystic ovary syndrome (PCOS).Subjects and methods: A high-performance liquid chromatography/time-of-flight mass spectrometry (HPLC/TOF-MS)-based metabolomics approach was developed to characterize the untargeted lipidomics signature associated with PCOS status in a discovery cohort of 30 plasma samples (15 PCOS, 15 controls, age-matched), followed in a s...